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Meltdown® Science: Combines the synergistic fat burning power of beta andrenergic agonists (MethylSynephrine) and alpha andrenergic antagonists (Yohimbine HCl, alpha-Yohimbine and 11-Hydroxy Yohimbine). In simpler terms it activates fat burning mechanisms in your body while simultaneously blocking the internal biochemistry that prevents you from burning fat by guarding one of the body’s key fat burning hormones called Norepinephrine (NE). When fat burning is both promoted and protected at the same time we call this effect "synergistic". So, instead of 9 (activation factor) + 8 (protection factor) equaling 17 on the fat burning scale, this synergistic combination has a geometric effect of 72!